VPS36 antibody

Catalog No. ABIN7467027

This Rabbit Polyclonal antibody specifically detects VPS36 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for VPS36 antibody (ABIN7467027)

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS36 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VPS36 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human VPS36. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.81 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for VPS36

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Alternative Name: vacuolar protein sorting 36 homolog

Background: Vacuolar protein sorting 36 homolog , C13orf9 , CGI-145 , EAP45,VPS36, VPS22 (SNF8, MIM 610904), and VPS25 (MIM 610907) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. VPS36, VPS22, and VPS25 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM]

Molecular Weight: 44 kDa

Gene ID: 51028

UniProt: Q86VN1