LGR5 antibody

Catalog No. ABIN7467196

The Mouse Monoclonal anti-LGR5 antibody has been validated for WB. It is suitable to detect LGR5 in samples from Human.

Quick Overview for LGR5 antibody (ABIN7467196)

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGR5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GT11312

Product Details anti-LGR5 Antibody

Specificity: Orthogonal validation was supported by references (PMID:30224759)

Cross-Reactivity: Human, Mouse

Purification: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LGR5. The exact sequence is proprietary.

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Alternative Name: leucine rich repeat containing G protein-coupled receptor 5

Background: Leucine rich repeat containing G protein-coupled receptor 5 , FEX , GPR49 , GPR67 , GRP49 , HG38,Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.

Molecular Weight: 100 kDa

Gene ID: 8549

UniProt: O75473

Pathways: WNT Signaling