CHMP6 antibody

Catalog No. ABIN7467301

The Rabbit Polyclonal anti-CHMP6 antibody has been validated for WB. It is suitable to detect CHMP6 in samples from Human.

Quick Overview for CHMP6 antibody (ABIN7467301)

Target: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHMP6 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CHMP6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CHMP6

Target: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Alternative Name: charged multivesicular body protein 6

Background: Charged multivesicular body protein 6 , VPS20,CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]

Molecular Weight: 23 kDa

Gene ID: 79643

UniProt: Q96FZ7