GLI1 antibody (C-Term)

Catalog No. ABIN7467396

This Rabbit Polyclonal antibody specifically detects GLI1 in WB, IF, ICC and ChIP-seq. It exhibits reactivity toward Mouse.

Quick Overview for GLI1 antibody (C-Term) (ABIN7467396)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-GLI1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse Gli1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: RMS13

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.57 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Alternative Name: GLI-Kruppel family member GLI1

Background: GLI-Kruppel family member GLI1 , AV235269 , Zfp-5 , Zfp5,May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.

Molecular Weight: 119 kDa

Gene ID: 14632

UniProt: P47806

Pathways: Hedgehog Signaling, Dopaminergic Neurogenesis