INTS4 antibody (N-Term)

Catalog No. ABIN7467567

This Rabbit Polyclonal antibody specifically detects INTS4 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for INTS4 antibody (N-Term) (ABIN7467567)

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-INTS4 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human INTS4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG , MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for INTS4

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Alternative Name: integrator complex subunit 4

Background: Integrator complex subunit 4 , INT4 , MST093,INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM]

Molecular Weight: 108 kDa

Gene ID: 92105

UniProt: Q96HW7

Pathways: SARS-CoV-2 Protein Interactome