Cadherin 5 antibody (N-Term)

Catalog No. ABIN7467896

This anti-Cadherin 5 antibody is a Mouse Monoclonal antibody detecting Cadherin 5 in WB, ICC, IF and IHC (p). Suitable for Human.

Quick Overview for Cadherin 5 antibody (N-Term) (ABIN7467896)

Target: Cadherin 5 (CDH5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GT1369

Product Details anti-Cadherin 5 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Affinity purified by Protein G.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human VE-Cadherin. The exact sequence is proprietary.

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: cadherin 5

Background: Cadherin 5 , 7B4 , CD144,This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]

Molecular Weight: 88 kDa

Gene ID: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2