AFG3L2 antibody (N-Term)

Catalog No. ABIN7467943

The Rabbit Polyclonal anti-AFG3L2 antibody has been validated for WB and IHC (p). It is suitable to detect AFG3L2 in samples from Human.

Quick Overview for AFG3L2 antibody (N-Term) (ABIN7467943)

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFG3L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AFG3L2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human AFG3L2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: SK-N-SH membrane fraction extract Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Alternative Name: AFG3 like matrix AAA peptidase subunit 2

Background:

Synonyms: AFG3 like matrix AAA peptidase subunit 2 , SCA28 , SPAX5

Background: This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq]

Molecular Weight: 89 kDa

Gene ID: 10939

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development