CD3G antibody (C-Term)

Catalog No. ABIN7468115

This anti-CD3G antibody is a Rabbit Polyclonal antibody detecting CD3G in WB, FACS and IHC (p). Suitable for Human.

Quick Overview for CD3G antibody (C-Term) (ABIN7468115)

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD3G antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD3G Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD3 gamma. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Molt-4

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CD3G

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Alternative Name: CD3g molecule

Background:

Synonyms: CD3g molecule , CD3-GAMMA , IMD17 , T3G

Background: The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq]

Molecular Weight: 20 kDa

Gene ID: 917

UniProt: P09693

Pathways: TCR Signaling, CXCR4-mediated Signaling Events