COPS3 antibody

Catalog No. ABIN7468167

This Rabbit Polyclonal antibody specifically detects COPS3 in WB, IF, IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for COPS3 antibody (ABIN7468167)

Target: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-COPS3 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human COPS3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for COPS3

Target: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Alternative Name: COP9 signalosome subunit 3

Background:

Synonyms: COP9 signalosome subunit 3 , CSN3 , SGN3

Background: The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq]

Molecular Weight: 48 kDa

Gene ID: 8533

UniProt: Q9UNS2

Pathways: Cell Division Cycle