COPS4 antibody

Catalog No. ABIN7468169

This anti-COPS4 antibody is a Rabbit Polyclonal antibody detecting COPS4 in WB, IHC (p), ICC and IF. Suitable for Human.

Quick Overview for COPS4 antibody (ABIN7468169)

Target: COPS4 (COP9 Signalosome Subunit 4 (COPS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-COPS4 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human COPS4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for COPS4

Target: COPS4 (COP9 Signalosome Subunit 4 (COPS4))

Alternative Name: COP9 signalosome subunit 4

Background:

Synonyms: COP9 signalosome subunit 4 , CSN4 , SGN4

Background: This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. [provided by RefSeq]

Molecular Weight: 46 kDa

Gene ID: 51138

UniProt: Q9BT78

Pathways: Cell Division Cycle