DZIP3 antibody

Catalog No. ABIN7468203

This Rabbit Polyclonal antibody specifically detects DZIP3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for DZIP3 antibody (ABIN7468203)

Target: DZIP3 (DAZ Interacting Protein 3, Zinc Finger (DZIP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DZIP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DZIP3 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DZIP3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.93 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DZIP3

Target: DZIP3 (DAZ Interacting Protein 3, Zinc Finger (DZIP3))

Alternative Name: DAZ interacting zinc finger protein 3

Background:

Synonyms: DAZ interacting zinc finger protein 3 , PPP1R66 , UURF2 , hRUL138

Background: E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.

Molecular Weight: 139 kDa

Gene ID: 9666

UniProt: Q86Y13