GATM antibody

Catalog No. ABIN7468379

This anti-GATM antibody is a Rabbit Polyclonal antibody detecting GATM in WB. Suitable for Human.

Quick Overview for GATM antibody (ABIN7468379)

Target: GATM (Glycine Amidinotransferase (GATM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GATM Antibody

Cross-Reactivity: Human, Mouse, Zebrafish (Danio rerio)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GATM. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GATM

Target: GATM (Glycine Amidinotransferase (GATM))

Alternative Name: glycine amidinotransferase

Background:

Synonyms: glycine amidinotransferase , AGAT , AT , CCDS3

Background: This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq]

Molecular Weight: 48 kDa

Gene ID: 2628

UniProt: P50440