GMP Synthase antibody

Catalog No. ABIN7468392

This Rabbit Polyclonal antibody specifically detects GMP Synthase in WB. It exhibits reactivity toward Human.

Quick Overview for GMP Synthase antibody (ABIN7468392)

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMP Synthase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GMP Synthase Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GMP synthase. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.69 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GMP Synthase

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Alternative Name: guanine monophosphate synthase

Background:

Synonyms: guanine monophosphate synthase , GATD7

Background: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq]

Molecular Weight: 77 kDa

Gene ID: 8833

UniProt: P49915

Pathways: Ribonucleoside Biosynthetic Process