CLDND1 antibody (AA 201-253)

Catalog No. ABIN719906

The Rabbit Polyclonal anti-CLDND1 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect CLDND1 in samples from Human.

Quick Overview for CLDND1 antibody (AA 201-253) (ABIN719906)

Target: CLDND1 (Claudin Domain Containing 1 (CLDND1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDND1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CLDND1 Antibody

Binding Specificity: AA 201-253

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLDND1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CLDND1

Target: CLDND1 (Claudin Domain Containing 1 (CLDND1))

Alternative Name: CLDND1

Background:

Synonyms: C3orf4, Chromosome 3 open reading frame 4, Claudin domain containing 1, Claudin domain containing 1 protein, Membrane protein GENX3745, CLDN1_HUMAN.

Background: CLDND1 is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Gene ID: 56650