Integrator Complex Subunit 13 (INTS13) antibody

Catalog No. ABIN7468483

The Rabbit Polyclonal anti-Integrator Complex Subunit 13 antibody is suitable to detect Integrator Complex Subunit 13 in samples from Human. It has been validated for ICC and IF.

Quick Overview for Integrator Complex Subunit 13 (INTS13) antibody (ABIN7468483)

Target: Integrator Complex Subunit 13 (INTS13)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human C12orf11. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.62 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: Integrator Complex Subunit 13 (INTS13)

Alternative Name: integrator complex subunit 13

Background:

Synonyms: integrator complex subunit 13 , ASUN , C12orf11 , GCT1 , Mat89Bb , NET48 , SPATA30

Background: Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267).

Molecular Weight: 80 kDa

Gene ID: 55726

UniProt: Q9NVM9