ITGAL antibody

Catalog No. ABIN7468487

This anti-ITGAL antibody is a Rat Monoclonal antibody detecting ITGAL in FACS. Suitable for Human.

Quick Overview for ITGAL antibody (ABIN7468487)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: GT0011

Product Details anti-ITGAL Antibody

Cross-Reactivity: Mouse

Purification: Affinity purified by Protein G.

Immunogen: The immunogen used to generate this antibody corresponds to human CD11a

Isotype: IgG2a

Application Details

Application Notes: FACS: 1:50-1:200. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: integrin subunit alpha L

Background:

Synonyms: integrin subunit alpha L , CD11A , LFA-1 , LFA1A

Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 129 kDa

Gene ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex