JARID2 antibody (N-Term)

Catalog No. ABIN7468503

This Rabbit Polyclonal antibody specifically detects JARID2 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for JARID2 antibody (N-Term) (ABIN7468503)

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JARID2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-JARID2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human JARID2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , human JARID2-transfected 293T cells , fetal mouse forebrain , HeLa Validation: Comparison, KO/KD, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for JARID2

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Alternative Name: jumonji and AT-rich interaction domain containing 2

Background:

Synonyms: jumonji and AT-rich interaction domain containing 2 , JMJ

Background: This gene is an ortholog of the mouse jumonji gene, which encodes a nuclear protein essential for mouse embryogenesis, including neural tube formation. Overexpression of mouse jumonji negatively regulates cell proliferation. The jumonji proteins contain a DNA-binding domain, called an AT-rich interaction domain (ARID), and share regions of similarity with human retinoblastoma-binding protein-2 and the human SMCX protein. [provided by RefSeq]

Molecular Weight: 139 kDa

Gene ID: 3720

UniProt: Q92833

Pathways: Chromatin Binding