KDM4A antibody (C-Term)

Catalog No. ABIN7468560

This Rabbit Polyclonal antibody specifically detects KDM4A in WB. It exhibits reactivity toward Human.

Quick Overview for KDM4A antibody (C-Term) (ABIN7468560)

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM4A Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human KDM4A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Rat brain , HeLa nuclear extract Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.84 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for KDM4A

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Alternative Name: lysine demethylase 4A

Background:

Synonyms: lysine demethylase 4A , JHDM3A , JMJD2 , JMJD2A , TDRD14A

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq]

Molecular Weight: 121 kDa

Gene ID: 9682

UniProt: O75164

Pathways: Warburg Effect