KDM6A antibody

Catalog No. ABIN7468568

This anti-KDM6A antibody is a Rabbit Polyclonal antibody detecting KDM6A in WB, IF, ICC, IP, ChIP and IHC (p). Suitable for Human.

Quick Overview for KDM6A antibody (ABIN7468568)

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM6A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-KDM6A Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human KDM6A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.68 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Alternative Name: lysine demethylase 6A

Background:

Synonyms: lysine demethylase 6A , KABUK2 , UTX , bA386N14.2

Background: This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. [provided by RefSeq]

Molecular Weight: 154 kDa

Gene ID: 7403

UniProt: O15550

Pathways: Tube Formation, Warburg Effect