MPP5 antibody (N-Term)

Catalog No. ABIN7468593

This Rabbit Polyclonal antibody specifically detects MPP5 in WB. It exhibits reactivity toward Human.

Quick Overview for MPP5 antibody (N-Term) (ABIN7468593)

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MPP5 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MPP5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MPP5

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Alternative Name: membrane palmitoylated protein 5

Background:

Synonyms: membrane palmitoylated protein 5 , PALS1

Background: Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1, MIM 601014), ZO1-like (see TJP1, MIM 601009), p55-like (see MPP1, MIM 305360), and LIN2-like (see CASK, MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001 [PubMed 11311936]). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM]

Molecular Weight: 77 kDa

Gene ID: 64398

UniProt: Q8N3R9

Pathways: Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization