NME3 antibody (C-Term)

Catalog No. ABIN7468669

The Rabbit Polyclonal anti-NME3 antibody has been validated for WB. It is suitable to detect NME3 in samples from Human.

Quick Overview for NME3 antibody (C-Term) (ABIN7468669)

Target: NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NME3 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human nm23-H3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NME3

Target: NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))

Alternative Name: NME/NM23 nucleoside diphosphate kinase 3

Background:

Synonyms: NME/NM23 nucleoside diphosphate kinase 3 , DR-nm23 , NDPK-C , NDPKC , NM23-H3 , NM23H3 , c371H6.2

Background: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.

Molecular Weight: 19 kDa

Gene ID: 4832

UniProt: Q13232

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process