PYGB antibody (N-Term)

Catalog No. ABIN7468745

This anti-PYGB antibody is a Rabbit Polyclonal antibody detecting PYGB in WB. Suitable for Human.

Quick Overview for PYGB antibody (N-Term) (ABIN7468745)

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYGB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PYGB Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human GPBB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji , Mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.57 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PYGB

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Alternative Name: glycogen phosphorylase B

Background:

Synonyms: glycogen phosphorylase B , GPBB

Background: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq]

Molecular Weight: 97 kDa

Gene ID: 5834

UniProt: P11216

Pathways: Cellular Glucan Metabolic Process