KCNK3 antibody

Catalog No. ABIN7468770

This Rabbit Polyclonal antibody specifically detects KCNK3 in WB. It exhibits reactivity toward Human.

Quick Overview for KCNK3 antibody (ABIN7468770)

Target: KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNK3 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human KCNK3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse lung , Jurkat membrane extract Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.61 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for KCNK3

Target: KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))

Alternative Name: potassium two pore domain channel subfamily K member 3

Background:

Synonyms: potassium two pore domain channel subfamily K member 3 , K2p3.1 , OAT1 , PPH4 , TASK , TASK-1 , TBAK1

Background: This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq]

Molecular Weight: 44 kDa

Gene ID: 3777

UniProt: O14649