SURF1 antibody

Catalog No. ABIN7469040

This Rabbit Polyclonal antibody specifically detects SURF1 in WB. It exhibits reactivity toward Human.

Quick Overview for SURF1 antibody (ABIN7469040)

Target: SURF1 (Surfeit 1 (SURF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SURF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SURF1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SURF1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SURF1

Target: SURF1 (Surfeit 1 (SURF1))

Alternative Name: SURF1 cytochrome c oxidase assembly factor

Background:

Synonyms: SURF1 cytochrome c oxidase assembly factor , CMT4K

Background: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq]

Molecular Weight: 33 kDa

Gene ID: 6834

UniProt: Q15526

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process