TRPS1 antibody

Catalog No. ABIN7469087

This anti-TRPS1 antibody is a Rabbit Polyclonal antibody detecting TRPS1 in WB and IHC (p). Suitable for Human.

Quick Overview for TRPS1 antibody (ABIN7469087)

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRPS1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TRPS1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:2500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7 , MCF-7 nuclear extract Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Alternative Name: transcriptional repressor GATA binding 1

Background:

Synonyms: transcriptional repressor GATA binding 1 , GC79 , LGCR

Background: This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq]

Molecular Weight: 142 kDa

Gene ID: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus