TRPS1 antibody (AA 90-170)

Catalog No. ABIN7224808

The Rabbit Polyclonal anti-TRPS1 antibody is suitable to detect TRPS1 in samples from Human and Mouse. It has been validated for IHC, ELISA, WB and IF.

Quick Overview for TRPS1 antibody (AA 90-170) (ABIN7224808)

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPS1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TRPS1 Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-TRPS1 Polyclonal Antibody

Specificity: TRPS1 Polyclonal Antibody detects endogenous levels of TRPS1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human TRPS1 at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Alternative Name: TRPS1

Background: TRPS1, Zinc finger transcription factor Trps1, Tricho-rhino-phalangeal syndrome type I protein, Zinc finger protein GC79TRPS1 (transcriptional repressor GATA binding 1) encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in TRPS1 are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.

Molecular Weight: 141kD

Gene ID: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus