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TSG101 antibody

This anti-TSG101 antibody is a Rabbit Polyclonal antibody detecting TSG101 in WB, ELISA, IP and IHC (p). Suitable for Human.
Catalog No. ABIN7469108

Quick Overview for TSG101 antibody (ABIN7469108)

Target

See all TSG101 Antibodies
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This TSG101 antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade

KO Validated
  • Cross-Reactivity

    Human, Mouse

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human TSG101. The exact sequence is proprietary.

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Comment

    Positive Control: 293T , U87-MG , SK-N-SH , IMR32 , SK-N-AS Validation: KO/KD

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.09 mg/mL

    Buffer

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    Alternative Name

    tumor susceptibility 101

    Background

    Synonyms: tumor susceptibility 101 , TSG10 , VPS23

    Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq]

    Molecular Weight

    44 kDa

    Gene ID

    7251

    UniProt

    Q99816
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