UGT2B7 antibody

Catalog No. ABIN7469126

This anti-UGT2B7 antibody is a Rabbit Polyclonal antibody detecting UGT2B7 in WB. Suitable for Human.

Quick Overview for UGT2B7 antibody (ABIN7469126)

Target: UGT2B7 (UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT2B7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UGT2B7 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human UGT2B7. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for UGT2B7

Target: UGT2B7 (UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7))

Alternative Name: UDP glucuronosyltransferase family 2 member B7

Background:

Synonyms: UDP glucuronosyltransferase family 2 member B7 , UDPGT 2B7 , UDPGT 2B9 , UDPGT2B7 , UDPGTH2 , UDPGTh-2 , UGT2B9

Background: The UGTs (EC 2.4.1.17) serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.[supplied by OMIM]

Molecular Weight: 61 kDa

Gene ID: 7364

UniProt: P16662

Pathways: Steroid Hormone Biosynthesis