Uncoupling Protein 1 antibody
Quick Overview for Uncoupling Protein 1 antibody (ABIN7469138)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Mouse
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Purification
- Affinity purified by Protein G.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human UCP1. The exact sequence is proprietary.
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Isotype
- IgG1
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Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: mouse brown adipose
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, No Preservative
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Preservative
- Without preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Uncoupling Protein 1
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Background
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Synonyms: uncoupling protein 1 , SLC25A7 , UCP
Background: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq]
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Molecular Weight
- 33 kDa
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Gene ID
- 7350
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UniProt
- P25874
Target
-
