ZWINT antibody

Catalog No. ABIN7469217

This Mouse Monoclonal antibody specifically detects ZWINT in WB. It exhibits reactivity toward Human.

Quick Overview for ZWINT antibody (ABIN7469217)

Target: ZWINT (ZW10 Interactor (ZWINT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZWINT antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GT276

Product Details anti-ZWINT Antibody

Cross-Reactivity: Human

Purification: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ZWINT. The exact sequence is proprietary.

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ZWINT

Target: ZWINT (ZW10 Interactor (ZWINT))

Alternative Name: ZW10 interacting kinetochore protein

Background:

Synonyms: ZW10 interacting kinetochore protein , HZwint-1 , KNTC2AP , SIP30 , ZWINT1

Background: This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 31 kDa

Gene ID: 11130

UniProt: O95229