FKBP5 antibody

Catalog No. ABIN7469367

This Rabbit Polyclonal antibody specifically detects FKBP5 in WB. It exhibits reactivity toward Human.

Quick Overview for FKBP5 antibody (ABIN7469367)

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FKBP5 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FKBP5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FKBP5

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Alternative Name: FKBP5

Background:

Synonyms: FKBP prolyl isomerase 5 , AIG6 , FKBP51 , FKBP54 , P54 , PPIase , Ptg-10

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq]

Molecular Weight: 51 kDa

Gene ID: 2289

UniProt: Q13451