HEY2 antibody (N-Term)

Catalog No. ABIN7469395

The Rabbit Polyclonal anti-HEY2 antibody has been validated for WB. It is suitable to detect HEY2 in samples from Human.

Quick Overview for HEY2 antibody (N-Term) (ABIN7469395)

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HEY2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human HEY2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549 , H1299 , HCT116 , MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HEY2

Background:

Synonyms: hes related family bHLH transcription factor with YRPW motif 2 , CHF1 , GRIDLOCK , GRL , HERP1 , HESR2 , HRT2 , bHLHb32

Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq]

Molecular Weight: 36 kDa

Gene ID: 23493

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation