PTF1A antibody (C-Term)

Catalog No. ABIN7469517

This Rabbit Polyclonal antibody specifically detects PTF1A in WB. It exhibits reactivity toward Human.

Quick Overview for PTF1A antibody (C-Term) (ABIN7469517)

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTF1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTF1A Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human PTF1A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: AsPC-1 Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PTF1A

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Alternative Name: PTF1A

Background:

Synonyms: pancreas associated transcription factor 1a , PACA , PAGEN2 , PTF1-p48 , bHLHa29 , p48

Background: This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq]

Molecular Weight: 35 kDa

Gene ID: 256297

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway