SENP5 antibody

Catalog No. ABIN7469623

The Rabbit Polyclonal anti-SENP5 antibody has been validated for WB. It is suitable to detect SENP5 in samples from Human.

Quick Overview for SENP5 antibody (ABIN7469623)

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SENP5 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SENP5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SENP5

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Alternative Name: SENP5

Background:

Synonyms: SUMO specific peptidase 5

Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM]

Molecular Weight: 87 kDa

Gene ID: 205564

UniProt: Q96HI0