VPS18 antibody (C-Term)

Catalog No. ABIN7469651

This anti-VPS18 antibody is a Rabbit Polyclonal antibody detecting VPS18 in WB, IF and ICC. Suitable for Human.

Quick Overview for VPS18 antibody (C-Term) (ABIN7469651)

Target: VPS18 (Vacuolar Protein Sorting 18 Homolog (VPS18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS18 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-VPS18 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human VPS18. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.36 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for VPS18

Target: VPS18 (Vacuolar Protein Sorting 18 Homolog (VPS18))

Alternative Name: VPS18

Background:

Synonyms: VPS18 core subunit of CORVET and HOPS complexes , PEP3

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq]

Molecular Weight: 110 kDa

Gene ID: 57617

UniProt: Q9P253

Pathways: Asymmetric Protein Localization