STING1 (AA 190-290) antibody

Catalog No. ABIN7477591

This anti- antibody is a Mouse Monoclonal antibody detecting in IHC. Suitable for Human.

Quick Overview for STING1 (AA 190-290) antibody (ABIN7477591)

Target: STING1

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Clone: MSVA-515M

Product Details

Binding Specificity: AA 190-290

Immunogen: Recombinant fragment (around aa190-290) of human TMEM173 protein (exact sequence is proprietary)

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Comment:

Positive Control: Adrenal gland: Endothelial cells and macrophages should show a moderate to strong STING positivity.

Negative Control: Adrenal gland: Adrenocortical and medullary cells should not show STING staining (Note: in case of tissue damage aberrant STING staining may occur).

Protocol: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer's directions.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non- hazardous.

Target Details

Target: STING1

Background: Endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, Mediator of IRF3 activation, MITA, NET23, MPYS, Mitochondrial mediator of IRF3 activation, N terminal methionine proline tyrosine serine plasma membrane tetraspanner, Stimulator of interferon genes protein, Transmembrane protein 173,STING1 antibody validated for immunohistochemistry on 76 different Normal Tissues

UniProt: Q86WV6