STING1 (AA 170-379) antibody

Catalog No. ABIN5701799

The Rabbit Polyclonal anti-STING1 antibody is suitable to detect STING1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA, FACS, IF and IP.

Quick Overview for STING1 (AA 170-379) antibody (ABIN5701799)

Target: STING1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details

Binding Specificity: AA 170-379

Purpose: STING1 antibody

Immunogen:

Immunogen sequence: 170-379aa

Immunogen: transmembrane protein 173

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08759(TMEM173 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details

Target: STING1

Background:

Synonyms: Stimulator of interferon genes protein (hSTING)|Endoplasmic reticulum interferon stimulator (ERIS)|Mediator of IRF3 activation (hMITA)|Transmembrane protein 173|STING1|ERIS|MITA|STING|TMEM173

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Gene ID: 340061

UniProt: Q86WV6