Recombinant Bevacizumab antibody (Biotin)
Quick Overview for Recombinant Bevacizumab antibody (Biotin) (ABIN7488554)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Clone
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Purpose
- Biotinylated Anti-Bevacizumab Antibody (AY13) (recommended for PK/PD)
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Characteristics
- Anti-idiotypic Antibodies
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Immunogen
- Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- -20 °C
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- Bevacizumab
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Target Type
- Antibody
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Background
- A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.
Target
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