Recombinant Bevacizumab antibody

Catalog No. ABIN7482170

The Mouse Monoclonal anti-Bevacizumab antibody is suitable to detect Bevacizumab in samples from Human.

Quick Overview for Recombinant Bevacizumab antibody (ABIN7482170)

Target: Bevacizumab

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Bevacizumab antibody is un-conjugated

Grade: MALS verified

Clone: AY10

Product Details anti-Bevacizumab Antibody

Purpose: Anti-Bevacizumab Antibody (AY10) (MALS verified, recommended for PK/PD)

Characteristics: Anti-idiotypic Antibodies

Immunogen: Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: -20 °C

Target Details for Bevacizumab

Target: Bevacizumab

Target Type: Antibody

Background: A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.