Recombinant ITGA4 (Natalizumab Biosimilar) antibody

Catalog No. ABIN7487736

The Mouse Chimeric anti-ITGA4 (Natalizumab Biosimilar) antibody has been validated for FACS and BR. It is suitable to detect ITGA4 (Natalizumab Biosimilar) in samples from Human.

Quick Overview for Recombinant ITGA4 (Natalizumab Biosimilar) antibody (ABIN7487736)

Target: ITGA4 (Natalizumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Chimeric

Conjugate: This ITGA4 (Natalizumab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Product Details anti-ITGA4 (Natalizumab Biosimilar) Antibody

Purpose: Anti-Integrin alpha 4 [Natalizumab], Mouse IgG1, kappa

Specificity: This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin

Characteristics:

Original Species of Ab: Human

Original Format of Ab: IgG4

Purification: Protein A affinity purified

Immunogen: The RAMOS cell line, a non-EBV releasing cell line, injected into mice.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.

Comment:

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for ITGA4 (Natalizumab Biosimilar)

Target: ITGA4 (Natalizumab Biosimilar)

Background: CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV

UniProt: P13612