Recombinant Mesothelin antibody

Catalog No. ABIN7487739

The Mouse Monoclonal anti-Mesothelin antibody is suitable to detect Mesothelin in samples from Human. It has been validated for WB, ELISA and IP.

Quick Overview for Recombinant Mesothelin antibody (ABIN7487739)

Target: Mesothelin (MSLN)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Mesothelin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Clone: 20-10

Product Details anti-Mesothelin Antibody

Purpose: Anti-MPF [20-10], Mouse IgG1, kappa

Specificity: This antibody binds the human megakaryocyte-potentiating factor.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant megakaryocyte potentiating factor protein.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody is recommended to be used in combination with mAb 41-28 for detecting megakaryote potentiating factor (MPF) with high sensitivity in a capture ELISA. This antibody can also immunoprecipitate recombinant MPF. The antibody can successfully detect MPF in a western blot assay (PMID: 24167356, 18394747).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for Mesothelin

Target: Mesothelin (MSLN)

Alternative Name: MPF

Background: Megakaryocyte-potentiating factor, MSLN, CAK1 antigen, mesothelin

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process