FCRL3 antibody

Catalog No. ABIN7505904

This Mouse Monoclonal antibody specifically detects FCRL3 in FACS. It exhibits reactivity toward Human.

Quick Overview for FCRL3 antibody (ABIN7505904)

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCRL3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: H5

Product Details anti-FCRL3 Antibody

Purpose: Anti-Hu CD307c Purified

Characteristics: The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.

Purification: Purified by protein-A affinity chromatography.

Immunogen: DNA-immunization followed by a boost with CD307c transfected cells

Isotype: IgG2b, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for FCRL3

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Alternative Name: CD307c

Background: Fc receptor like 3,CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.,FcRL3, IRTA3

Gene ID: 115352

UniProt: Q96P31