SIGLEC9 antibody

Catalog No. ABIN7505917

The Mouse Monoclonal anti-SIGLEC9 antibody is suitable to detect SIGLEC9 in samples from Human. It has been validated for WB, ELISA, FACS, ICC and IP.

Quick Overview for SIGLEC9 antibody (ABIN7505917)

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIGLEC9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: K8

Product Details anti-SIGLEC9 Antibody

Purpose: Anti-Hu CD329 Purified

Characteristics: The mouse monoclonal antibody K8 recognizes an extracellular epitope of CD239, a type I transmembrane glycoprotein expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells.

Purification: Purified by protein-A affinity chromatography.

Immunogen: recombinant CD329-Hu IgGFc fusion protein

Isotype: IgG1, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for SIGLEC9

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Alternative Name: CD329

Background: Sialic acid binding Ig like lectin 9,CD329 is a type I transmembrane glycoprotein of siglec family, which contains intracellular ITIM motif, and a SLAM-like motif, that acts as a docking site for SAP. CD329 can regulate TCR signaling by recruitment of SHP-1, which results in down-regulation of TCR-based gene transcription. It is expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells, weaker expression is detectable in some B cells, NK cells, and T cells.,SIGLEC9

Gene ID: 27180

UniProt: Q9Y336