ITGA6 antibody (PE)

Catalog No. ABIN7505941

The Rat Monoclonal anti-ITGA6 antibody has been validated for FACS. It is suitable to detect ITGA6 in samples from Human, Mouse, Dog, Cow, Pig, Sheep, Horse, Rabbit, Cat and Non-Human Primate.

Quick Overview for ITGA6 antibody (PE) (ABIN7505941)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human, Mouse, Dog, Cow, Pig, Sheep, Horse, Rabbit, Cat, Non-Human Primate

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: GoH3

Product Details anti-ITGA6 Antibody (PE)

Purpose: Anti-CD49f PE

Specificity: The rat monoclonal antibody GoH3 recognizes an extracellular epitope of CD49f, an alpha6 integrin subunit.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: mouse mammary tumor cells

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: CD49f

Background: Integrin subunit alpha 6,CD49f (alpha 6 integrin) is a type I transmembrane glycoprotein, which noncovalently associates with CD29 (beta 1 integrin) to form VLA-6, and with CD104 (beta 4 integrin) to form alpha6/beta4 integrin complex. CD49f is expressed on platelets, megakaryocytes, monocytes, T cells and thymocytes. It is widely expressed on many cultured adherent cell lines and on epithelia in non-lymphoid tissues. It is important for adhesion to laminins, invasin, and merosin, hence also for cell migration, embryogenesis, metastasis, formation of hemidesmosomes in epithelia, and other processes.,ITGA6, VLA6alpha, platelet gpIc, integrin subunit alpha 6

Gene ID: 3655

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex