OLR1 antibody (Extracellular Domain)

Catalog No. ABIN7505992

The Mouse Monoclonal anti-OLR1 antibody is suitable to detect OLR1 in samples from Human. It has been validated for ICC, FACS and IHC (fro).

Quick Overview for OLR1 antibody (Extracellular Domain) (ABIN7505992)

Target: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OLR1 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 15C4

Product Details anti-OLR1 Antibody

Binding Specificity: Extracellular Domain

Purpose: Anti-Hu LOX1 Purified

Characteristics: The mouse monoclonal antibody 15C4 recognizes an extracellular epitope of LOX1, a C-type lectin transmembrane protein.

Purification: Purified by protein-A affinity chromatography.

Immunogen: fusion protein of human LOX1 ectodomain and of human IgG Fc

Isotype: IgG2a, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-5 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for OLR1

Target: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Alternative Name: LOX1

Background: Oxidized low density lipoprotein receptor 1,LOX1, a 31 kDa type II transmembrane protein, is a C-type lectin, functioning as a scavenger receptor for e.g. oxidized low density lipoprotein, apoptotic heat shock proteins, or CRP. It is expressed by macrophages, fibroblasts, platelets, endothelial cells, and smooth muscle cells, and its defects can lead to atherosclerosis. Its expression is enhanced under inflammatory conditions. Multiple splicing variants have been identified.,OLR1, SLOX1, SCARE1, CLEC8A

Gene ID: 4973

UniProt: P78380