PODXL antibody
Quick Overview for PODXL antibody (ABIN7506005)
Target
See all PODXL AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu PODXL Purified
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Specificity
- The mouse monoclonal antibody PcMab-47 recognizes a glycosylation-dependent epitope (aa 207-210) on human PODXL, a highly glycosylated transmembrane glycoprotein expressed above all in many types of cancer tissues, and on embryonic stem cells.
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Purification
- Purified by protein-A affinity chromatography.
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Immunogen
- recombinant PODXL ectodomain
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Isotype
- IgG1 kappa
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Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- PODXL (Podocalyxin-Like (PODXL))
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Alternative Name
- PODXL
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Background
- Podocalyxin like,PODXL is a highly glycosylated sialomucin, which is expressed in many types of tumors, as well as it is a well known marker of embryonic stem cells. Overexpression of PODXL is an independent predictor of cancer progression, metastasis, and poor outcome. PODXL promotes tumor growts and invasiveness, and is a potential target for antibody therapy.,PCLP-1, Gp200, podocalyxin like
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Gene ID
- 5420
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UniProt
- O00592
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Pathways
- Tube Formation
Target
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