RNF115 antibody (AA 161-260) (HRP)

Catalog No. ABIN720979

This Rabbit Polyclonal antibody specifically detects RNF115 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RNF115 antibody (AA 161-260) (HRP) (ABIN720979)

Target: RNF115 (Ring Finger Protein 115 (RNF115))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF115 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RNF115 Antibody (HRP)

Binding Specificity: AA 161-260

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BCA2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNF115

Target: RNF115 (Ring Finger Protein 115 (RNF115))

Alternative Name: BCA2

Background:

Synonyms: BCA2, Breast cancer associated gene 2, CL469780, Rabring 7, RING finger protein 115, RNF115, Zinc finger protein 364, RN115_HUMAN.

Background: The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.