MME antibody (APC-iFluor™ 750)

Catalog No. ABIN7529004

The Mouse Monoclonal anti-MME antibody has been validated for FACS. It is suitable to detect MME in samples from Human.

Quick Overview for MME antibody (APC-iFluor™ 750) (ABIN7529004)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is conjugated to APC-iFluor™ 750

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: C-1A12

Product Details anti-MME Antibody (APC-iFluor™ 750)

Purpose: CD10 APC-iFluor™ 750 Antibody

Characteristics: The clone C-1A12, a mouse monoclonal antibody recognizes a 100 kDa protein that has neutral metalloendopeptidase activity and inactivates a variety of biologically active peptides known as CD10. CD10 is type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. CD10 plays important role in the development process of B cells the in germinal center. This protein is not restricted to leukemic cells. Normal, healthy precursors of B and T cells and granulocytes also express CD10.

Purification: Purified

Purity: >95 %

Immunogen: Purified cell membrane antigens from fresh leukemia cells.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10

Gene ID: 4311

NCBI Accession: NC_000003

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration