Recombinant 4-1BB (Utomilumab Biosimilar) antibody

Catalog No. ABIN7538049

The Human Monoclonal anti-4-1BB (Utomilumab Biosimilar) antibody is suitable to detect 4-1BB (Utomilumab Biosimilar) in samples from Human. It has been validated for ELISA and WB.

Quick Overview for Recombinant 4-1BB (Utomilumab Biosimilar) antibody (ABIN7538049)

Target: 4-1BB (Utomilumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This 4-1BB (Utomilumab Biosimilar) antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Grade: Research Grade

Product Details anti-4-1BB (Utomilumab Biosimilar) Antibody

Expression System: Mammalian cells

Purpose: Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade

Characteristics: Antibody Type: IgG2 kappa

Purification: Recombinant antibody expressed in mammalien cells and purified.

Purity: > 85%

Isotype: IgG2

Application Details

Restrictions: For Research Use only

Handling

Buffer: PBS pH 7.5

Storage: 4 °C,-20 °C

Storage Comment: 4°C for short term, -20°C for long term

Target Details for 4-1BB (Utomilumab Biosimilar)

Target: 4-1BB (Utomilumab Biosimilar)

Background: Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.

CAS-No: 1417318-27-4