Cadherin-16 antibody

Catalog No. ABIN7539849

This Mouse Monoclonal antibody specifically detects Cadherin-16 in IHC, WB, FACS, ELISA and ICC. It exhibits reactivity toward Human.

Quick Overview for Cadherin-16 antibody (ABIN7539849)

Target: Cadherin-16 (CDH16)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Clone: 6H6E2

Product Details anti-Cadherin-16 Antibody

Purpose: CDH16 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CDH16 (AA: EX(558-721)) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: CDH16

Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Molecular Weight: 90 kDa

UniProt: O75309